Meningeal inflammation and multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Meningeal Gd-DTPA enhancement in multiple sclerosis.
Although the cause of demyelination in multiple sclerosis (MS) remains obscure, inflammation invariably is present. Demyelination in MS is accompanied by lymphoplasmocytic infiltration of retinal veins (1), cerebral white matter, and meninges (2-4). In vivo demonstration of infiltration of the retina can be observed on ophthalmoscopy and by means of fluorescein angiography (1). In vivo demonstr...
متن کاملMeningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis.
Meningeal inflammation in the form of ectopic lymphoid-like structures has been suggested to play a prominent role in the development of cerebral cortical grey matter pathology in multiple sclerosis. The aim of this study was to analyse the incidence and distribution of B cell follicle-like structures in an extensive collection of cases with secondary progressive multiple sclerosis with a wide ...
متن کاملMeningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis.
Cortical demyelination can be extensive in chronic multiple sclerosis (MS) patients. Cortical lesions are not associated with lymphocyte infiltration, blood-brain barrier disruption, or complement deposition; therefore, their pathogenesis is unclear. We analyzed the extent and cellular composition of leptomeningeal inflammatory infiltrates and their relationship with cortical demyelinated lesio...
متن کاملIn-vivo imaging of meningeal inflammation in multiple sclerosis: Presence of evidence or evidence of presence?
Recent histopathology studies suggest the presence of meningeal inflammation in patients with multiple sclerosis (MS) that might be associated with subpial cortical demyelination and a rather worse disease course.1 Although a radiologist is not a pathologist, diagnostic neuroradiology aims to visualize and to detect almost every (subtle) pathological feature of a disease to its full extent. To ...
متن کاملMeningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis.
The primary progressive form of multiple sclerosis is characterized by accrual of neurological dysfunction from disease onset without remission and it is still a matter of debate whether this disease course results from different pathogenetic mechanisms compared with secondary progressive multiple sclerosis. Inflammation in the leptomeninges has been identified as a key feature of secondary pro...
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ژورنال
عنوان ژورنال: Neuroimmunology and Neuroinflammation
سال: 2016
ISSN: 2349-6142,2347-8659
DOI: 10.20517/2347-8659.2016.22